Defense Co-Counsel
Profile
Marc Agnifilo is a prominent New York criminal defense attorney and co-founder of Agnifilo Intrater LLP who, alongside his wife Karen Friedman Agnifilo, joined the defense team for Luigi Mangione in the UnitedHealthcare CEO murder case. Previously a partner at Brafman & Associates for over a decade, Agnifilo has represented clients in some of the country's most complex criminal trials, securing acquittals in cases ranging from assault to international tax fraud. He and Karen Friedman Agnifilo formed one of the most high-profile husband-wife legal teams in the Mangione proceedings.
UnitedHealthcare CEO Shooting
Defense Co-Counsel
On December 4, 2024, UnitedHealthcare CEO Brian Thompson was fatally shot outside the New York Hilton Midtown in what prosecutors allege was a premeditated attack by Luigi Mangione, a 26-year-old University of Pennsylvania graduate. Mangione was arrested five days later at a McDonald's in Altoona, Pennsylvania, after a nationwide manhunt, and charged with second-degree murder in New York state court and stalking charges in federal court. As of April 2026, Mangione has pleaded not guilty to all charges; his state trial is scheduled to begin September 8, 2026, and his federal trial is set for October 2026, with a federal judge having ruled that prosecutors cannot seek the death penalty.
Luigi Mangione Gets Spared; Death Penalty Taken off the Table as he faces charges for Murder of CEO
Luigi Mangione: STS Files · Feb 3, 2026 · 22m
BARD - Don Lemon, Luigi Mangione, and the Limits of Federal Power
Reasonable Doubt · Feb 1, 2026 · 20m
Reacting To This ABSURD Story Regarding Luigi Mangione
The Valenti Show · Jan 29, 2026 · 7m
Luigi Mangione - Part Two: On Pain of Death | #432
RedHanded · Jan 15, 2026 · 1h 9m
Does Luigi Mangione have a ‘real shot?’; rumors in Tepe's murders | Banfield Full Episode 1/9
Banfield · Jan 11, 2026 · 41m
Luigi Mangione - Part One: “Deny, Defend, Depose” | #431
RedHanded · Jan 8, 2026 · 56m
Luigi Mangione's Defense Argue Arrest Details & Body Cam Video Concerns May Jeopardize a Fair Trial
Luigi Mangione: STS Files · Dec 24, 2025 · 19m
Back In Court on Anniversary of CEO Killing: Will Key Evidence Be Thrown Out In Luigi Mangione Trial
Luigi Mangione: STS Files · Dec 24, 2025 · 22m
What Really Happened in That McDonald’s: Mangione’s Breakdown Exposed-WEEK IN REVIEW
United Healthcare Murder: The Luigi Mangione Story · Dec 14, 2025 · 41m
The Case Against Luigi Mangione | Vinnie Politan Investigates Podcast
Court TV Podcast · Dec 13, 2025
Ret FBI Coffindaffer Breaks Down Two Murderous Narcissists: Luigi Mangione & Brian Walshe
United Healthcare Murder: The Luigi Mangione Story · Dec 10, 2025 · 51m
What Luigi Mangione Carried, What Brian Walshe Hid, and What Happened to Pregnant Mother Rebecca Park
True Crime Tonight · Dec 9, 2025 · 1h 34m
BOMBSHELL: Here's Why Luigi Mangione Will Get Off! w/ Nick Cruse
The Jimmy Dore Show · Dec 5, 2025 · 1h 1m
Was Key Luigi Mangione Evidence Illegal? Inside His Courtroom War
United Healthcare Murder: The Luigi Mangione Story · Dec 3, 2025 · 23m
Luigi Mangione Could Have a Chance... Pre-Trial Motions in Luigi Mangione Case
Crime Talk with Scott Reisch · Dec 1, 2025 · 44m
The Luigi Mangione Evidence Battle; ’Tis the Season… to Get Duped?
Here's the Scoop · Dec 1, 2025 · 20m
NO FIRST-DEGREE MURDER CHARGES AGAINST LUIGI MANGIONE?
Crime Stories with Nancy Grace · Nov 30, 2025 · 43m
I Saw Luigi Mangione In Court & This Is EVERYTHING That Happened
Rotten Mango · Oct 5, 2025 · 1h 25m
From Overcharged to Death Penalty: Luigi Mangione & Tyler Robinson Updates
United Healthcare Murder: The Luigi Mangione Story · Sep 17, 2025 · 1h 7m
Behind the memes: Luigi Mangione and Brian Thompson
The Mangione Trial · May 7, 2025 · 25m
Who is Luigi Mangione and what’s he accused of?
The Mangione Trial · Feb 18, 2025 · 27m
The 5,000% Markup: How UnitedHealth Profits from Cancer Patients
Delay, Deny, Depose: Luigi Mangione and the Assassination of UnitedHealthcare CEO Brian Thompson · Jan 18, 2025 · 8m
3 Dec 2024 - Arraignment Hearing
Full Trial Audio: Luigi Mangione · Jan 2, 2025 · 10m
Luigi Mangione: Unraveling the Alleged United Healthcare CEO Assassin
Killer Psyche · Dec 24, 2024 · 54m
Federal Criminal Complaint Against Luigi Mangione (SDNY, Dec 2024)
US District Court, SDNY · Dec 18, 2024
3/ DisCypher: Inside the Mind of Tech Prodigy Luigi Mangione
Delay, Deny, Depose: Luigi Mangione and the Assassination of UnitedHealthcare CEO Brian Thompson · Dec 13, 2024 · 5m
Arrest in UnitedHealthcare CEO murder. Drama at a Georgia sentencing. And Josh Mankiewicz on "Deadly Mirage."
Dateline NBC · Dec 12, 2024 · 28m
Luigi Mangione- The Man Behind the Murder of UnitedHealthcare CEO
Luigi Mangione · Dec 11, 2024 · 5m
Delay, Deny, Defend: Why Insurance Companies Don't Pay Claims and What You Can Do About It
Jay Feinman · Sep 7, 2010
UnitedHealthcare CEO shooting suspect's timeline before, during, after the brazen murder
ABC News
